Chlorination of 2-phenoxypropanoic acid with NCP in aqueous acetic acid: Using a novel ortho-para relationship and the para/meta ratio of substituent effects for …

…, JDG de Oliveira, S Kabilan, M Shanthi

文献索引：Segurado, Manuel A. P.; Reis, Joao Carlos R.; De Oliveira, Jaime D. Gomes; Kabilan, Senthamaraikannan; Shanthi, Manohar Journal of Organic Chemistry, 2007 , vol. 72, # 14 p. 5327 - 5336

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被引用次数: 5

摘要

Rate constants were measured for the oxidative chlorodehydrogenation of (R, S)-2- phenoxypropanoic acid and nine ortho-, ten para-and five meta-substituted derivatives using (R, S)-1-chloro-3-methyl-2, 6-diphenylpiperidin-4-one (NCP) as chlorinating agent. The kinetics was run in 50%(v/v) aqueous acetic acid acidified with perchloric acid under pseudo- first-order conditions with respect to NCP at temperature intervals of 5 K between 298 and ...