Chemical Communications 2003-01-07

Reaction of ADP with amino acid methyl esters mediated by trimethylsilyl chloride.

Hua Fu, Bo Han, Yu-Fen Zhao

文献索引：Chem. Commun. (Camb.) (1) , 134-5, (2003)

全文：HTML全文

摘要

Reaction of ADP with amino acid methyl esters mediated by trimethylsilyl chloride in pyridine produced adenosine 5'-phosphoramidates in good yields under mild conditions, it is interesting that nucleophilic attack of amino acid methyl esters only occurred on alpha-phosphorus of ADP.