Abstract Decarboxylation of allylic esters of 4-carboxypyrimidines in toluene at 111 C in the presence of a Pd (0) catalyst, gives a mixture of a 4-alkenylpyrimidine and a pyrimidine unsubstituted in the 4-position. If the decarboxylation is carried out in the presence of benzaldehyde, then benzaldehyde is added to the 4-position. Decarboxylation of 4- carboxypyrimidines in the presence of different electrophiles, results in incorporation of ...
