Journal of the American Chemical Society

4-Thio and 2, 4-Dithio 5, 5-Dialkylthiobarbituric Acids

JH Boothe, CO Wilson

文献索引：Boothe; Wilson Journal of the American Chemical Society, 1946 , vol. 68, p. 449

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被引用次数: 4

摘要

Early in the history of barbituric acid synthesis, a fe. w 2-thiobarbiturates were prepared for the purpose of converting them into the corresponding oxygen analogs. In fact, Fischer and Dilthey2 reported the preparation of 5, s-diethyl-% thiobarbituric acid in their original paper in 1904. Until 1935, however, no systematic attempt was made to prepare a series of these compounds and evaluate them pharmacologically. This was probably due to the fact that ...