Fluoroanalogs of DDT: superacidic BF3–H2O catalyzed facile synthesis of 1, 1, 1-trifluoro-2, 2-diarylethanes and 1, 1-difluoro-2, 2-diarylethanes

GKS Prakash, F Paknia, T Mathew, G Mlostoń…

文献索引：Prakash, G. K. Surya; Paknia, Farzaneh; Mathew, Thomas; Mloston, Gzregorz; Joschek, Jens P.; Olah, George A. Organic Letters, 2011 , vol. 13, # 15 p. 4128 - 4131

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被引用次数: 24

摘要

The one-pot synthesis of 1, 1, 1-trifluoro-and 1, 1-difluoro-2, 2-diarylethanes from arenes and fluorinated hemiacetals in the BF3–H2O system is described. The reaction is simple, clean, and convenient, eliminating the use of organic solvents and other expensive acid systems. BF3–H2O is economic, is easy to prepare, and offers ample acidity required for this reaction.