Toxicology Letters 2013-11-25

Crotonaldehyde induces heat shock protein 72 expression that mediates anti-apoptotic effects in human endothelial cells

Dong Sun Ryu, Hana Yang, Seung Eun Lee, Cheung-Seog Park, Young-Ho Jin, Yong Seek Park

文献索引：Toxicol. Lett. 223(2) , 116-23, (2013)

摘要

• Crotonaldehyde induces HSP72 up-regulation in HUVECs. • HSP72 induction is mediated by JNK-HSF1 pathway. • HSP72 expression by crotonaldehyde requires calcium ions and ROS. • Up-regulation of HSP72 protects against crotonaldehyde-induced apoptosis in HUVECs.

结构式	名称/CAS号	分子式	全部文献
	3,6-二氧杂-1,8-辛二胺四乙酸(EGTA) CAS:67-42-5	C₁₄H₂₄N₂O₁₀
	巴豆醛 CAS:4170-30-3	C₄H₆O
	1,2-双(2-氨基苯氧基)乙烷-N,N,N',N'-四乙酸 CAS:85233-19-8	C₂₂H₂₄N₂O₁₀
	2-丁烯醛 CAS:123-73-9	C₄H₆O

Crotonaldehyde induces heat shock protein 72 expression that mediates anti-apoptotic effects in human endothelial cells

摘要

相关化合物