Chemical Communications 2011-08-28

Simple synthesis of 1,3-cyclopentanedione derived probes for labeling sulfenic acid proteins.

Jiang Qian, Chananat Klomsiri, Marcus W Wright, S Bruce King, Allen W Tsang, Leslie B Poole, Cristina M Furdui

文献索引：Chem. Commun. (Camb.) 47(32) , 9203-5, (2011)

摘要

Facile, two-step synthesis and kinetic characterization of new chemical probes for selective labeling of sulfenic acid (-SOH) in proteins are presented. The synthesis route relies on the simple and highly efficient Michael addition of thiol containing tags or linkers to 4-cyclopentene-1,3-dione, the unsaturated derivative of 1,3-cyclopentanedione.

结构式	名称/CAS号	分子式	全部文献
	1,3-环戊二酮 CAS:3859-41-4	C₅H₆O₂
	4-环戊烯-1,3-二酮 CAS:930-60-9	C₅H₄O₂

SAR and 3D-QSAR studies on thiadiazolidinone derivatives: ex...
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Simple synthesis of 1,3-cyclopentanedione derived probes for labeling sulfenic acid proteins.

摘要

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