Regioselective hydration and deprotection of chiral, dissymmetric iminodinitriles in the scope of an asymmetric Strecker strategy

…, M Marull, L Boiteau, J Taillades

文献索引：Rossi, Jean-Christophe; Marull, Marc; Boiteau, Laurent; Taillades, Jacques European Journal of Organic Chemistry, 2007 , # 4 p. 662 - 668

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被引用次数: 7

摘要

Abstract The controlled, selective decomposition of dissymmetric iminodinitriles (DIDN) of formula RCH (CN)–NH–C (CN) R′ R ″(considered as N-protected alpha-aminonitriles), is a critical issue for an original asymmetric Strecker strategy previously outlined by us for the enantioselective synthesis of amino acids. This strategy, derived from Harada's work, involves a double sequence of (i) stereoselective Strecker condensation of a chiral ketone ...