Tetrahedron Letters

1, 4-Cyclohexadiene with Pd/C as a rapid, safe transfer hydrogenation system with microwave heating

JF Quinn, DA Razzano, KC Golden, BT Gregg

文献索引：Quinn, John F.; Razzano, Dana A.; Golden, Kathryn C.; Gregg, Brian T. Tetrahedron Letters, 2008 , vol. 49, # 42 p. 6137 - 6140

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被引用次数: 38

摘要

A method for the rapid, safe hydrogenation of alkenes and deprotection of benzyl ethers and carboxybenzyl amides is described using catalytic transfer hydrogenation under microwave heating conditions. Commonly available Pd/C catalyst is extremely effective with 1, 4- cyclohexadiene as the hydrogen transfer source. In general, the reactions are complete within five minutes at 100° C.