Tetrahedron letters

A novel 1-tert-butoxy-2-tert-butoxycarbonyl-1, 2-dihydroisoquinoline (BBDI)-catalyzed esterification of N-protected amino acids with nearly equimolar amounts of …

Y Saito, T Watanabe, H Takahata

文献索引：Saito, Yukako; Watanabe, Tomokazu; Takahata, Hiroki Tetrahedron Letters, 2006 , vol. 47, # 18 p. 3099 - 3102

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被引用次数: 7

摘要

Ester moieties constitute major backbones, as well as important functional groups, in numerous natural products and synthetic compounds. 1 In addition, ester groups are also useful protecting groups for carboxylic acids in chemical synthesis. 2 Esterification is defined as the transformation of carboxylic acids or their derivatives into esters. A major problem that is frequently encountered in esterification technology arises from equilibration. To shift the equilibrium to the product ...