Amino Acids 1999-01-01

A new protection/activation strategy for the synthesis of naturally occurring and non-natural alpha-N-alkylamino acids.

K Burger, H Schedel, J Spengler

文献索引：Amino Acids 16(3-4) , 287-95, (1999)

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摘要

A new method for the preparation of N-methylamino acids and some of their derivatives starting from hexafluoroacetone protected amino acids is described. The new concept results in saving of steps compared to conventional protection/activation techniques. Protection and deprotection proceed without recemization.