Xenobiotica 1980-12-01

Metabolism of limonene-1,2-epoxide in the rat.

J W Regan, M M Morris, B Nao, L F Bjeldanes

文献索引：Xenobiotica 10(12) , 859-61, (1980)

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摘要

1. The metabolism of limonene-1,2-epoxide was studied following intraperitoneal injection in rats and in rat liver homogenates. 2. Limonene-1,2-glycol was the only neutral metabolite detected. Major limonene metabolites, p-mentha-2,8-dien-1-alpha and -beta-ol and p-mentha-1,8-dien-6-alpha and -beta-ol were not observed. 3. Limonene-1,2-epoxide is not a major intermediate in limonene metabolism in the rat.