Aminocarbonylation of (Hetero) aryl Bromides with Ammonia and Amines using a Palladium/DalPhos Catalyst System

PG Alsabeh, M Stradiotto, H Neumann…

文献索引：Alsabeh, Pamela G.; Stradiotto, Mark; Neumann, Helfried; Beller, Matthias Advanced Synthesis and Catalysis, 2012 , vol. 354, # 16 p. 3065 - 3070

全文：HTML全文

被引用次数: 17

摘要

Abstract Variants of the DalPhos [2-aminophenylbisadamantyl) phosphine] ligand family were examined in a palladium-catalyzed carbonylative amination reaction using inexpensive carbon monoxide and ammonia as reagents. As a result of this survey, the Pyr- DalPhos ligand was identified as being effective for the selective aminocarbonylation of aryl bromides with ammonia, as well as primary and secondary alkylamines. A variety of ...