Efficient one-pot synthesis of the 2-aminocarbonylpyrrolidin-4-ylthio-containing side chain of the new broad-spectrum carbapenem antibiotic ertapenem

KMJ Brands, RB Jobson, KM Conrad…

文献索引：Matsumura, Haruki; Bando, Takashi; Sunagawa, Makoto Heterocycles, 1995 , vol. 41, # 1 p. 147 - 160

全文：HTML全文

被引用次数: 28

摘要

... Volume: Page: ... A triple-resonance NMR experiment ( 13 C observed with simultaneous 1 H and 31 P decoupling) was used to verify these ... Significant sym-anhydride formation obviously detracts from the maximum achievable yield for 10 in this process. ...