Emil Rudolf, Miroslav Cervinka
文献索引:Toxicol. Lett. 204(2-3) , 164-73, (2011)
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Highlights ► Zinc pyrithione (ZnPyr) is cytotoxic in human dermal fibroblasts. ► High ZnPyr induces p53- and p38-dependent response and mitochondrial apoptosis. ► Low ZnPyr induces weak stress response without affecting mitogenic signaling. ► Low ZnPyr stimulates premature senescence in dermal fibroblasts.