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General and highly efficient syntheses of m-fluoro arenes using potassium fluoride-exchange method

H Suzuki, N Yazawa, Y Yoshida, O Furusawa…

文献索引:Suzuki, Hiroshi; Yazawa, Naoto; Yoshida, Yasuo; Furusawa, Osamu; Kimura, Yoshikazu Bulletin of the Chemical Society of Japan, 1990 , vol. 63, # 7 p. 2010 - 2017

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被引用次数: 46

摘要

Tetraphenylphosphonium bromide was found to be a suitable catalyst for the reaction of m- nitroaryl derivatives carrying cyano, nitro, chlorocarbonyl, trifluoromethyl, and chlorosulfonyl groups with potassium fluoride in the presence of a stoichiometric amount of phthaloyl dichloride, giving the corresponding m-fluoro aromatic derivatives in good yields. The catalyst was also found to be efficient for the fluorodesulfonylation of m-(fluorosulfonyl) ...

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