Synthesis, Structure, and Glutathione Peroxidase??Like Activity of Amino Acid Containing Ebselen Analogues and Diaryl Diselenides

K Selvakumar, P Shah, HB Singh…

文献索引：Selvakumar, Karuthapandi; Shah, Poonam; Singh, Harkesh B.; Butcher, Ray J. Chemistry - A European Journal, 2011 , vol. 17, # 45 p. 12741 - 12755

全文：HTML全文

被引用次数: 43

摘要

Abstract The synthesis of some ebselen analogues and diaryl diselenides, which have amino acid functions as an intramolecularly coordinating group (Se⋅⋅⋅ O) has been achieved by the DCC coupling procedure. The reaction of 2, 2′-diselanediylbis (5-tert- butylisophthalic acid) or the activated ester tetrakis (2, 5-dioxopyrrolidin-1-yl) 2, 2′- diselanediylbis (5-tert-butylisophthalate) with different C-protected amino acids (Gly, L- ...