2-(Diethylamino) ethanethiol, a new reagent for the odorless deprotection of aromatic methyl ethers

…, MH Chen, JD Clark, T Nussbaumer

文献索引：Magano, Javier; Chen, Michael H.; Clark, Jerry D.; Nussbaumer, Thomas Journal of Organic Chemistry, 2006 , vol. 71, # 18 p. 7103 - 7105

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被引用次数: 42

摘要

A new reagent for the deprotection of aromatic methyl ethers, 2-(diethylamino) ethanethiol, is reported. This compound, commercially available as its HCl salt, affords the corresponding phenols in good to excellent yields on a wide variety of substrates. A clear advantage of this method over the use of more common thiols, such as ethanethiol, is the easy extraction of both the deprotecting reagent and the byproduct 2-(diethylamino) ethyl methyl sulfide into ...