Synthesis of O-allyl derivatives of 2, 3-dihydroxypropyluracil and thymine and their antiviral activity

MS Novikov, AA Ozerov, AK Brel', EI Boreko…

文献索引：Novikov, M. S.; Ozerov, A. A.; Brel', A. K.; Boreko, E. I.; Vladyko, G. V.; Korobchenko, L. V. Pharmaceutical Chemistry Journal, 1991 , vol. 25, # 12 p. 880 - 883 Khimiko-Farmatsevticheskii Zhurnal, 1991 , vol. 25, # 12 p. 35 - 37

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被引用次数: 3

摘要

Earlier we detected high antiviral activity in allyloxyalkyl derivatives of uracil [2]. Therefore the investigation of the influence of the O-allyl fragments in the side chain of 2, 3- dihydroxypropyl derivatives of pyrimidine bases on their antiviral action is of considerable interest. In the present work, we describe the synthesis and the results of the examination of the antiviral activity of certain O-allyl derivatives of pyrimidine analogs of I. l-(3-Allyloxy-2- ...