Short and efficient access to imidazo [1, 2-a] pyrrolo [3, 2-c] pyridine derivatives

…, J Paeshuyse, C Lartigue, O Chavignon, A Gueiffier…

文献索引：Gaumet, Vincent; Moreau, Emmanuel; Taleb, Abbass; Leal, Fernand; Neyts, Johan; Paeshuyse, Jan; Lartigue, Claire; Chavignon, Olivier; Gueiffier, Alain; Teulade, Jean-Claude; Metin, Jacques; Chezal, Jean-Michel Tetrahedron Letters, 2010 , vol. 51, # 47 p. 6082 - 6085

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被引用次数: 3

摘要

Access to N-protected or N-free imidazo [1, 2-a] pyrrolo [3, 2-c] pyridine derivatives as potential antiviral compounds was achieved in good yields from N-protected 7-amino-8-halo- 2-methylimidazo [1, 2-a] pyridines by catalytic coupling of terminal acetylenes under mild conditions using [PdCl2 (PPh3) 2] or [Cu (Phen)(PPh3) 2] NO3.