Discovery of N-(4-(3-Amino-1 H-indazol-4-yl) phenyl)-N'-(2-fluoro-5-methylphenyl) urea (ABT-869), a 3-Aminoindazole-Based Orally Active Multitargeted Receptor …
Y Dai, K Hartandi, Z Ji, AA Ahmed…
文献索引：Journal of Medicinal Chemistry, , vol. 50, # 7 p. 1584 - 1597
... Journal of Medicinal Chemistry. ... From this series, a clinical candidate, 17p (ABT-869), was identified. In this paper, we report the rational design, chemical synthesis, and structure−activity relationships of this novel series as well as in vitro and in vivo properties of 17p. ...
