A useful prostanoid synthon, 7-(2-hydroxy-5-oxo-1-cyclopentenyl) heptanoic acid (3), was prepared from commercially available cyclooctanone in two steps. Nine other related cyclopentanoids which are also valuable synthons for prostaglandins were obtained from 3 in reasonable yields via several steps. The procedure is capable of generating these useful synthons on a laboratory scale.
![3-bromo-2-[6-(methoxycarbonyl)hexyl]-2-cyclopenten-1-one结构式](https://image.chemsrc.com/caspic/098/107220-02-0.png)