Synthesis of a scaffold for the creation of non-peptide libraries

A Kasal, L Kohout, M Lebl

文献索引：Kasal, Alexander; Kohout, Ladislav; Lebl, Michal Collection of Czechoslovak Chemical Communications, 1995 , vol. 60, # 12 p. 2147 - 2155

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被引用次数: 16

摘要

Recently, Ernest et al.1 used a naphthalene derivative as a scaffold for the construction of protein β-turn mimics, later for the same purpose Hirschmann2,3 employed a disub- stituted steroid derivative as a scaffold. Disubstituted steroid molecule was employed successfully for the construction of libraries of synthetic receptors4. We have conceived the use of a scaffold for the generation of non-peptide libraries (for discussion of various library approaches see eg5–7) which ...