Selective oxidation with N-bromosuccinimide. II. Cholestane-3β, 5α, 6β-triol

LF Fieser, S Rajagopalan

文献索引：Fieser; Rajagopalan Journal of the American Chemical Society, 1949 , vol. 71, p. 3938,3940

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被引用次数: 176

摘要

Huang-Minlon; the over-all yield is 68%. The oxidizing agent is more selective than chromic acid, bromine or even N-bromoacetamide, for the alcoholic groups at CS and CIZ remain unattacked in the presence of an excess. In consequence, desoxycholic acid can be prepared with greater efficiency and ease than heretofore by direct application of the procedure to the total crude acids of saponified bile. CONVERSE MEMORIAL LABORATORY CAMBRIDGE 38, ...