Synthesis and biological evaluation of new carbohydrate-substituted indenoisoquinoline topoisomerase I inhibitors and improved syntheses of the experimental …
DE Beck, K Agama, C Marchand…
文献索引：Kahn Chemische Berichte, 1885 , vol. 18, p. 3365
... Volume: Page: ... Within the indolocarbazole class, glycosylation is a critical feature for Top1 inhibitory activity, and its absence severely compromises potency.(18, 19) Attachment of a carbohydrate moiety to the indenoisoquinoline system has the potential to ...
