e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synthesis and biological evaluation of new carbohydrate-substituted indenoisoquinoline topoisomerase I inhibitors and improved syntheses of the experimental …
DE Beck, K Agama, C Marchand…
Index: Kahn Chemische Berichte, 1885 , vol. 18, p. 3365
... Volume: Page: ... Within the indolocarbazole class, glycosylation is a critical feature for Top1 inhibitory activity, and its absence severely compromises potency.(18, 19) Attachment of a carbohydrate moiety to the indenoisoquinoline system has the potential to ...
