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Vitamin E chemistry. Nitration of non-α-tocopherols: products and mechanistic considerations

A Patel, F Liebner, T Netscher, K Mereiter…

文献索引:Patel, Anjan; Liebner, Falk; Netscher, Thomas; Mereiter, Kurt; Rosenau, Thomas Journal of Organic Chemistry, 2007 , vol. 72, # 17 p. 6504 - 6512

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被引用次数: 43

摘要

In contrast to the α-form permethylated at the aromatic ring, non-α-tocopherols possess free aromatic ring positions which enable them to act as potent scavengers of electrophiles in vivo and in vitro. In preparation of enzymatic studies involving peroxynitrite and other nitrating systems, the behavior of non-α-tocopherols under nitration conditions was studied. The nitration products of β-, γ-, and δ-tocopherol were identified, comprehensively ...