Vitamin E chemistry. Nitration of non-α-tocopherols: products and mechanistic considerations

A Patel, F Liebner, T Netscher, K Mereiter…

Index: Patel, Anjan; Liebner, Falk; Netscher, Thomas; Mereiter, Kurt; Rosenau, Thomas Journal of Organic Chemistry, 2007 , vol. 72, # 17 p. 6504 - 6512

Full Text: HTML

Citation Number: 43

Abstract

In contrast to the α-form permethylated at the aromatic ring, non-α-tocopherols possess free aromatic ring positions which enable them to act as potent scavengers of electrophiles in vivo and in vitro. In preparation of enzymatic studies involving peroxynitrite and other nitrating systems, the behavior of non-α-tocopherols under nitration conditions was studied. The nitration products of β-, γ-, and δ-tocopherol were identified, comprehensively ...