2-Substituted [1] benzopyrano [4, 3-d] pyrimidin-5-ones

I Strakova, M Petrova, S Belyakov…

文献索引：Strakova; Petrova; Belyakov; Strakovs Chemistry of Heterocyclic Compounds, 2007 , vol. 43, # 6 p. 793 - 798

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被引用次数: 4

摘要

Abstract A new method is reported for the synthesis of 2-R-substituted [1] benzopyrano [4, 3- d] pyrimidin-5-ones (R= p-phenyl, p-chlorophenyl-, p-carbamoylphenyl-, 3-pyridinyl-, 4- pyridinyl-, 2-pyrazinyl-, pyrrolidino-, morpholino-, 3, 6-dimethyl-1-pyrazolyl-) by the reaction of 4-chloro-3-formylcoumarin with salts of the corresponding amidines RC (= NH) NH 2 HX in DMF in the presence of piperidine or triethylamine. 3-Formyl-4-coumarin and 2- ...