Experimental and theoretical insights into the mechanisms of sulfate and sulfamate ester hydrolysis and the end products of type I sulfatase inactivation by aryl …

SJ Williams, E Denehy, EH Krenske

文献索引：Williams,A.; Douglas,K.T. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1974 , p. 1727 - 1732

全文：HTML全文

被引用次数: 10

摘要

Type I sulfatases catalyze the hydrolysis of sulfate esters through S–O bond cleavage and possess a catalytically essential formylglycine (FGly) active-site residue that is post- translationally derived from either cysteine or serine. Type I sulfatases are inactivated by aryl