Photodegradation and photostability-indication of mequitazine

EM Abdel-Moety, MA Ibrahim, MR Rezk

文献索引：Abdel-Moety, Ezzat M.; Ibrahim, Mohamed A.; Rezk, Mamdouh R. Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2009 , vol. 74, # 3 p. 740 - 745

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被引用次数: 1

摘要

The photochemical behavior is investigated for mequitazine (MQ) illustrating possible mechanisms and photodegradation products formed. Accelerated photolysis is done for MQ under justified stress conditions by subjecting aqueous drug solutions to radiation for specified period of time. Synthesis of the main photodegradants, the sulfoxide, is achieved. Selective quantification of MQ, singly in bulk form, pharmaceutical formulations and/or in ...