Synthesis of new polyfunctional 5, 6, 7, 8-tetrahydroimidazo-[1, 5-c] pyrimidin-5-ones by the aza-Wittig reaction followed by intramolecular cyclization and 1, 3- …
…, VV Polovinko, AA Tolmachev, MV Vovk
文献索引：Lebed; Kos; Polovinko; Tolmachev; Vovk Russian Journal of Organic Chemistry, 2009 , vol. 45, # 6 p. 921 - 927
Abstract Ethyl 2-oxo-6-[(triphenyl-λ 5-phosphanylidene) aminomethyl]-1, 2, 3, 4- tetrahydropyrimidine-5-carboxylates reacted with organic isocyanates according to the aza- Wittig pattern, and the subsequent intramolecular ring closure and 1, 3-H shift resulted in the formation of ethyl 3-alkyl (aryl) amino-5-oxo-5, 6, 7, 8-tetrahydroimidazo [1, 5-c] pyrimidine-8- carboxylates.
