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Cerium catalysed Michael addition to alpha, beta-unsaturated oximes: A facile and efficient synthesis of substituted pyridines

S Kumar, A Saini, JS Sandhu

文献索引:Kumar, Sanjay; Saini, Anil; Sandhu, Jagir S. Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 2 p. 429 - 432

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被引用次数: 1

摘要

CeCl3.7H2O-NaI is found to be an effective catalyst for the synthesis of various tetra-substituted pyridine derivatives via Michael addition of β−dicarbonyl compounds to α,β–unsaturated oximes and subsequent ring closure by cyclo-dehydration of these products. ... Keywords: Cerium, Michael addition, unsaturated oximes, pyridines ... Michael reaction is a very important and useful method of carbon-carbon bond formation in organic chemistry. The classical version of this ...