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Copper-Mediated Sequential Cyanation of Aryl C–B and Arene C–H Bonds Using Ammonium Iodide and DMF

J Kim, J Choi, K Shin, S Chang

文献索引:Kim, Jinho; Choi, Jiho; Shin, Kwangmin; Chang, Sukbok Journal of the American Chemical Society, 2012 , vol. 134, # 5 p. 2528 - 2531

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被引用次数: 105

摘要

The cyanation of aromatic boronic acids, boronate esters, and borate salts was developed under copper-mediated oxidative conditions using ammonium iodide and DMF as the source of nitrogen and carbon atom of the cyano unit, respectively. The procedure was successfully extended to the cyanation of electron-rich benzenes, and regioselective introduction of a cyano group at the arene C–H bonds was also achieved. The ...

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