The ozonation of 4-thiopyrimidine and 6-thiopurine nucleosides in presence of amines afforded selectively and under mild experimental conditions several cytidine and adenosine nucleosides. The same reaction carried out in presence of alcohols afforded O4-or O6- alkylated derivatives of the nucleosides.
[Peacock, Hayden; Fucini, Raymond V.; Jayalath, Prasanna; Ibarra-Soza, Jose M.; Haringsma, Henry J.; Flanagan, W. Michael; Willingham, Aarron; Beal, Peter A. Journal of the American Chemical Society, 2011 , vol. 133, # 24 p. 9200 - 9203]
