Chemistry of carbanions. XVIII. Preparation of trimethylsilyl enol ethers

HO House, LJ Czuba, M Gall…

文献索引：House,H.O. et al. Journal of Organic Chemistry, 1969 , vol. 34, # 8 p. 2324 - 2336

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被引用次数: 677

摘要

Two procedures for the preparation of trimethylsilyl enol ethers from aldehydes and ketones are described. Reaction of the ketone with chlorotrimethylsilane and triethylamine in dimethylformamide solution usually affords an equilibrium mixture of the trimethylsilyl enol ethers. Successive reaction of the ketone with lithium diisopropylamide and with chlorotrimethyhilane in l12-dimethoxyethane solution normally produces a mixture in ...