CsOH-promoted chemoselective mono-N-alkylation of diamines and polyamines

…, SE Schmidt, SI Shin, AS Nagle, JH Worrell, KW Jung

文献索引：Salvatore; Schmidt; Shin; Nagle; Worrell; Jung Tetrahedron Letters, 2000 , vol. 41, # 50 p. 9705 - 9708

全文：HTML全文

被引用次数: 36

摘要

Naturally occurring diamines and polyamines have attracted considerable attention in synthetic organic chemistry due to their interesting biological activities, 1 potential pharmacological applications, 2 and asymmetric catalysis. 3 However, their synthetic use is quite limited mainly due to lack of efficient methods for monofunctionalization, although this problem has been averted by employing amines in large excess, which can be rather expensive. Recently, we ...