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Solid-phase synthesis of multiple classes of peptidomimetics from versatile resin-bound aldehyde intermediates

WL Scott, JG Martynow, JC Huffman…

文献索引:Pourahmady, N.; Palaniswamy, V. A.; Eisenbraun, E. J. Organic Magnetic Resonance, 1983 , vol. 21, # 11 p. 670 - 671

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被引用次数: 32

摘要

... Volume: Page: ... in order to attach an unnatural side chain to a resin-bound α-amino acid or peptide: (a) activation of the N-terminal residue ... 2.1.1. Preparation of Lactones 2. One of the simplest scaffolds available from 1 is lactone 2 (Scheme 1). 20,21 An example ...