Journal of Organic Chemistry

Friedel-Crafts cyclialkylations of certain mono-and diphenyl-substituted alcohols and alkyl chlorides

AA Khalaf, RM Roberts

文献索引：Khalaf,A.A.; Roberts,R.M. Journal of Organic Chemistry, 1972 , vol. 37, # 26 p. 4227 - 4235

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被引用次数: 50

摘要

Compounds 1-14 were prepared and cyclized under Friedel-Crafts conditions. The results of these cyclizations demonstrated that (I) ring closure at secondary carbons to tetralins takes precedence over ring closure at tertiary carbons to both indans and benzosuberanes (compounds 2-6);(2) ring closure at benzylic secondary carbon to a benzosuberane takes precedence over ring closure at an ordinary secondary carbon to a tetralin (compound 10) ...