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Transformation of the sydnone ring into oxadiazolinones. A convenient one-pot synthesis of 3-aryl-5-methyl-1, 3, 4-oxadiazolin-2-ones from 3-arylsydnones and their …

SG Mallur, BV Badami

文献索引：Mallur, Shanta G.; Badami, Bharati V. Farmaco, 2000 , vol. 55, # 1 p. 65 - 67

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被引用次数: 44

摘要

3-Arylsydnones (Ia–u) have been converted into the corresponding 3-aryl-5-methyl-1, 3, 4- oxadiazolin-2-ones (IIIa–u) by a single-step reaction with bromine in acetic anhydride. In the preliminary screening of all these compounds, the halogen-substituted derivatives have shown antimicrobial activities equal to those of the standard drugs used.