Synlett

Transition metal complexes in organic synthesis, part 74: Total synthesis of the marine alkaloid 6-chlorohyellazole

HJ Knölker, W Froehner, R Heinrich

文献索引：Knoelker, Hans-Joachim; Froehner, Wolfgang; Heinrich, Renate Synlett, 2004 , # 15 p. 2705 - 2708

被引用次数: 19

摘要

Abstract A considerably improved iron-mediated synthesis leads to the marine carbazole alkaloid hyellazole on large scale in eight steps and 63% overall yield from 2, 6- dimethoxytoluene. The first conversion of hyellazole into 6-chlorohyellazole has been achieved along with remarkably regiospecific halogenation reactions.

5673-07-4

2,6-二甲氧基甲苯

~87%

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