Tetrahedron

Tobramycin analogues with C-5 aminoalkyl ether chains intended to mimic rings III and IV of paromomycin

S Hanessian, M Tremblay, EE Swayze

文献索引：Hanessian, Stephen; Tremblay, Martin; Swayze, Eric E. Tetrahedron, 2003 , vol. 59, # 7 p. 983 - 993

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被引用次数: 47

摘要

Based on available X-ray structural and modeling data, a series of tobramycin derivatives with C-5 ether chains bearing basic groups were synthesized. These were intended to be hybrid molecules that combine features of tobramycin and paromomycin. Their binding to ...