Search for no donors. Part I. 3-Quinuclidone oximes

LN Koikov, NV Alekseeva, NB Grigor'ev…

文献索引：Koikov; Alekseeva; Grigor'ev; Levina; Turchin; Filipenko; Mashkovskii; Kaminka; Nikitin; Engalycheva; Kalinkina; Granik; Severina; Ryaposova Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 5 p. 243 - 250

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摘要

Identification of the "endothelial relaxation factor" as the endogenic NO formed from L-arginine in the vascular endo- thelium [1] has stimulated the search for new generation of cardiovascular drugs [2- 5]. At present, it has been estab- lished that biochemical synthesis of NO proceeds by different pathways. Exogenic organic nitrates (nitroglycerin, nitrosor- bid, and other classical vasodilators) are subject to reduction [6], as well as the new NO precursors such as N- ...