Identification of the "endothelial relaxation factor" as the endogenic NO formed from L-arginine in the vascular endo- thelium [1] has stimulated the search for new generation of cardiovascular drugs [2- 5]. At present, it has been estab- lished that biochemical synthesis of NO proceeds by different pathways. Exogenic organic nitrates (nitroglycerin, nitrosor- bid, and other classical vasodilators) are subject to reduction [6], as well as the new NO precursors such as N- ...