Tetrahedron letters

Chemoselective oxidation of primary alcohols to aldehydes with Gluconobacter oxydans

R Villa, A Romano, R Gandolfi, JVS Gago, F Molinari

文献索引：Villa, Raffaella; Romano, Andrea; Gandolfi, Raffaella; Sinisterra Gago, Jose V.; Molinari, Francesco Tetrahedron Letters, 2002 , vol. 43, # 34 p. 6059 - 6061

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被引用次数: 39

摘要

The production of aliphatic and aromatic aldehydes by oxidation of primary alcohols was achieved with Gluconobacter oxydans DSM 2343. The biotransformation was optimised studying the oxidation of 2-phenyl-1-ethanol to 2-phenylacetaldehyde. A high molar conversion (95% chromatographic conversion, 83% of isolated yield) was obtained using cells grown on glycerol as the main carbon source and directly used in the cultural ...