An update on the chemistry and medicinal chemistry of novel antimycobacterial compounds

F Silva Castelo Branco, AC Pinto…

文献索引：Polaroid Corporation Patent: US4652635 A1, 1987 ;

全文：HTML全文

被引用次数: 6

摘要

... Bedaquiline was synthesized for the original patent through a low-complexity route with 4 steps ... and circular dichroism, the stereogenic centers were determined for the enantiomer A1 (1R, 2S ... as OPC-67683) was devel- oped by the Japanese laboratory Otsuka, patented in 2004 ...