Organic letters

Ligand-Accelerated Pd-Catalyzed Ketone γ-Arylation via C–C Cleavage with Aryl Chlorides

A Ziadi, R Martin

文献索引：Ziadi, Asraa; Martin, Ruben Organic Letters, 2012 , vol. 14, # 5 p. 1266 - 1269

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被引用次数: 36

摘要

A highly efficient Pd-catalyzed arylative ring expansion of cyclobutanols via C–C bond cleavage is presented. The method allows the coupling of aryl chlorides at low catalyst loadings with a wide range of functional groups and substitution patterns, thus constituting a straightforward alternative for preparing rather elusive γ-arylated ketones.