Syntheses and applications of fluorescent and biotinylated epolactaene derivatives: Epolactaene and its derivative induce disulfide formation

…, R Matsui, A Morita, Y Mizushina, K Sakaguchi…

文献索引：Kuramochi, Kouji; Yukizawa, Shunsuke; Ikeda, Seiki; Sunoki, Takashi; Arai, Satoshi; Matsui, Rie; Morita, Akinori; Mizushina, Yoshiyuki; Sakaguchi, Kengo; Sugawara, Fumio; Ikekita, Masahiko; Kobayashi, Susumu Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 9 p. 5039 - 5049

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被引用次数: 8

摘要

Epolactaene, isolated from cultured Penicillium sp. BM 1689-P mycelium, induces neurite outgrowth and arrests the cell cycle of the human neuroblastoma cell line, SH-SY5Y, at the G1 phase. We have found that epolactaene and its derivatives induce apoptosis in the human leukemia B-cell line, BALL-1. In this study, we prepared fluorescent and biotinylated epolactaene derivatives. We characterized the cellular location and the identification of ...