Design and synthesis of piperazine-based matrix metalloproteinase inhibitors

M Cheng, B De, S Pikul, NG Almstead…

文献索引：Journal of Medicinal Chemistry, , vol. 43, # 3 p. 369 - 380

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被引用次数: 97

摘要

... Journal of Medicinal Chemistry. ... 6 The distal nitrogen atom (4N) of the piperazine ring provided the desired site for SAR work reported in this publication. figure Chart 1. Hydroxamic Acid-Based MMPIs. Chemistry. The ...