Design and synthesis of piperazine-based matrix metalloproteinase inhibitors

M Cheng, B De, S Pikul, NG Almstead…

Index: Journal of Medicinal Chemistry, , vol. 43, # 3 p. 369 - 380

Full Text: HTML

Citation Number: 97

Abstract

... Journal of Medicinal Chemistry. ... 6 The distal nitrogen atom (4N) of the piperazine ring provided the desired site for SAR work reported in this publication. figure Chart 1. Hydroxamic Acid-Based MMPIs. Chemistry. The ...